Characterization of Carbapenem-Resistant Enterobacteriaceae from Patients Stool in Tertiary Hospitals, Port Harcourt, Rivers State, Nigeria

Carbapenem-resistant Enterobacteriacaeae (CRE) are a serious new public-health problem. Carbapenem medicines class of antibiotics that often used to treat severe infections caused by bacteria antibiotic-resistant. The goal this study was use both conventional and molecular methods isolate, characterize, identify Enterobacteriaceae from stool samples patients at two tertiary hospitals in Port Harcourt, Rivers State, Nigeria. A total 114 feacal were collected inoculated onto Eosin methylene blue (EMB) agar MacConkey (M.A) plates. plates incubated for 24-48 hours. Representative colonies after incubation isolated subjected phenotypic characterisation using Biochemical Test, followed antibiotic susceptibility testing. Further done subjecting the isolates analysis. In study, 52 enteric organisms identified; 32 females while 20 males. gender distribution these showed Enteric more predominant than males with male subjects having E. coli 7 (35.0%), Klebsiella spp Salmonella 2 (10%), Shigella (10%) Pseudomonas female had 12 (37.5%), 13 (40.6%), 3 (9.4%), (9.4%) 1 (3.1%). Results recorded highest frequency (38.5%), 19 (36.5%), 5 (9.6%), 5(9.6%) (5.8%). pattern all very susceptible ciprofloxacin ofloxacin. Although meropenem high sensitivity organisms, ofloxacin recommended treatment since they have higher activities against bacteria.